I can add one small data point from home roasting. The Java Preanger beans I buy green are grown high up around Pangalengan and they are hard, and the same bag behaves differently depending on how dark I take it in the popper.
At a light roast they shatter in my hand grinder and give a lot of fines, so for V60 I go about two clicks coarser than for the darker batches of the same beans, dose unchanged at 15 g. The darker roast is more brittle and grinds more evenly at the normal setting. So in my case roast level moved the grind more than the origin did.
I agree with the last post, keep the dose fixed and change one thing at a time, otherwise you never know which change helped.